Correction: Intraflagellar transport (IFT) cargo
نویسندگان
چکیده
منابع مشابه
Intraflagellar transport (IFT) cargo
Intraflagellar transport (IFT) is the bidirectional movement of multisubunit protein particles along axonemal microtubules and is required for assembly and maintenance of eukaryotic flagella and cilia. One posited role of IFT is to transport flagellar precursors to the flagellar tip for assembly. Here, we examine radial spokes, axonemal subunits consisting of 22 polypeptides, as potential cargo...
متن کاملIntraflagellar transport (IFT) cargo: IFT transports flagellar precursors to the tip and turnover products to the cell body
Due to a printer error, Figure 9 was mislabeled. The bottom-center panel should have read " HA-RSP3 " instead of " Acetylated tubulin. " The corrected figure appears below. ntraflagellar transport (IFT) is the bidirectional movement of multisubunit protein particles along axonemal micro-tubules and is required for assembly and maintenance of eukaryotic flagella and cilia. One posited role of IF...
متن کاملUnderstanding cargo specificity in intraflagellar transport.
Cilia biogenesis and maintenance depends on intraflagellar transport (IFT) that at the same time mediates shuttling of cell-type-specific cargo. Mechanistic understanding of how the general IFT transport machinery links to the movement of specific ciliary cargo remains sparse. In this issue of The EMBO Journal, Zhao and Malicki (2011) show that two components of the IFT machinery (Fleer and IFT...
متن کاملIntraflagellar transport (IFT) during assembly and disassembly of Chlamydomonas flagella
Intraflagellar transport (IFT) of particles along flagellar microtubules is required for the assembly and maintenance of eukaryotic flagella and cilia. In Chlamydomonas, anterograde and retrograde particles viewed by light microscopy average 0.12-microm and 0.06-microm diameter, respectively. Examination of IFT particle structure in growing flagella by electron microscopy revealed similar size ...
متن کاملChlamydomonas Kinesin-II–dependent Intraflagellar Transport (IFT): IFT Particles Contain Proteins Required for Ciliary Assembly in Caenorhabditis elegans Sensory Neurons
We previously described a kinesin-dependent movement of particles in the flagella of Chlamydomonas reinhardtii called intraflagellar transport (IFT) (Kozminski, K.G., K.A. Johnson, P. Forscher, and J.L. Rosenbaum. 1993. Proc. Natl. Acad. Sci. USA. 90:5519-5523). When IFT is inhibited by inactivation of a kinesin, FLA10, in the temperature-sensitive mutant, fla10, existing flagella resorb and ne...
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ژورنال
عنوان ژورنال: The Journal of Cell Biology
سال: 2004
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.20040302164255